| 摘要 |
<p>Genomic DNA regions of avipoxviruses (hereinafter referred to as APVs) having at least two foreign genes in the genomic regions nonessential for the proliferation of the APVs: recombinant APVs carrying the above-mentionned genomic DNA regions integrated thereinto and having substantially the same proliferation properties as those of the parent strains; vaccines comprising these APVs; and a method for producing the above-mentionned recombinant APVs and a method for screening the same. Various foreign genes can be integrated into the genomic DNA regions as described above, which makes these regions usable as tools for integrating foreign genes over a considerably wide range into viruses usable in the construction of recombinant viruses via homologous integration.</p> |
