beta -lactam compounds

摘要

Compounds of the formula <IMAGE> I where Z, A, and R are as disclosed herein and pharmaceutically compatible, readily hydrolyzable esters and salts of these compounds are disclosed. The compounds have beta -lactamase inhibiting properties and are useful in the control of beta -lactamase-forming pathogens in combination with beta -lactam antibiotics. They also exhibit antibacterial activity of their own and can accordingly be used themselves in the control or treatment of infectious diseases.