发明名称 Histidine derivatives
摘要 The invention provides new compounds, derived from histidine, with the general formula (I), in which: n is 0 to 3; R represents one to five ring substituents which can be the same or different and are chosen independently of each other from the group consisting of hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, lower haloalkyl, lower haloalkoxy, lower alkyl thio, hydrothio, amino, alkylamino, dialkylamino, nitro, cyano, azido, amido. The compounds according to the invention exhibit neurotoxic and fluorescent activity and are thus particularly suitable as aids in the control of histaminergic neurons and of the neurotransmitter histamine. <IMAGE>
申请公布号 NL9201831(A) 申请公布日期 1994.05.16
申请号 NL19920001831 申请日期 1992.10.21
申请人 VRIJE UNIVERSITEIT 发明人
分类号 A61K49/00;C07D233/54;C09K11/06;G01N33/567;(IPC1-7):C07D233/64;A61K49/02;G01N33/52;G01N33/58 主分类号 A61K49/00
代理机构 代理人
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