发明名称 |
Immunotherapy of tumor with monoclonal antibody against the 17-1A antigen |
摘要 |
<p>A murine monoclonal antibody which specifically binds to an epitope of 17-1A antigen (or of a mixture of at least two of such antibodies)is used for the manufacture of a medicament for treating gastrointestinal tumor (e.g. gastrointestinal adenocarcinoma, colorectal or pancreatic carcinoma) by the parenteral administration (e.g. by intravenous infusion) of multiple doses of at least 100 milligrams or more per dose for a total dose of 0.1-5 grams (e.g. 1-5 grams) of antibody. Novel murine monoclonal antibodies are also described.</p> |
申请公布号 |
EP0755683(A1) |
申请公布日期 |
1997.01.29 |
申请号 |
EP19960202773 |
申请日期 |
1987.07.09 |
申请人 |
CENTOCOR, INC. |
发明人 |
SCHOEMAKER, HUBERT J.P.;CARRANO, RICHARD A. |
分类号 |
C12N15/02;A61K31/00;A61K35/00;A61K38/00;A61K39/395;A61P35/00;A61P37/00;C07K14/005;C07K14/195;C07K16/00;C07K16/30;C12N15/00;C12P21/00;C12P21/08;(IPC1-7):A61K39/395 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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