发明名称 チロシンキナーゼ阻害剤
摘要 The present disclosure provides compounds and pharmaceutically acceptable salts thereof that are tyrosine kinase inhibitors, in particular BLK, BMX, EGFR, HER2, HER4, ITK, TEC, BTK, and TXK and are therefore useful for the treatment of diseases treatable by inhibition of tyrosine kinases such as cancer and inflammatory diseases such as arthritis, and the like. Also provided are pharmaceutical compositions containing such compounds and pharmaceutically acceptable salts thereof and processes for preparing such compounds and pharmaceutically acceptable salts thereof.
申请公布号 JP5974084(B2) 申请公布日期 2016.08.23
申请号 JP20140511480 申请日期 2012.05.16
申请人 プリンシピア バイオファーマ インコーポレイテッド 发明人 ゴールドスタイン,デイビッド マイケル;ブラメルド,ケネス アルバート
分类号 C07D487/04;A61K31/519;A61K31/5377;A61K45/00;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P29/00;A61P35/00;A61P35/02;A61P37/06;A61P43/00 主分类号 C07D487/04
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