发明名称 |
Reagens für endotoxinspezifischen Assay |
摘要 |
Disclosed are a reagent for endotoxin-specific assay which comprises an insoluble carrier having immobilized thereon at least an endotoxin-sensitive factor derived from a limulus amebocyte; a kit for endotoxin-specific assay containing said reagent and a substrate for activated factor C or a substrate for clotting enzyme; a method for assaying endotoxin comprising applying a sample solution to said reagent to cause endotoxin in the sample to react with factor C in said reagent and determining a change of a substrate; and a process for preparing said reagent which comprises physically or chemically immobilizing at least an endotoxin-sensitive factor derived from a limulus amebocyte on an insoluble carrier. Endotoxin in a sample, even turbid or colored, can be specifically assayed with ease and rapidness without the influence of a (1->3)- beta -glucan. <IMAGE> |
申请公布号 |
DE69327211(D1) |
申请公布日期 |
2000.01.13 |
申请号 |
DE1993627211 |
申请日期 |
1993.09.14 |
申请人 |
SEIKAGAKU KOGYO K.K., TOKIO/TOKYO |
发明人 |
TANAKA, SHIGENORI;TAMURA, HIROSHI;OHKI, MAKOTO |
分类号 |
G03C5/50;G01N33/545;G01N33/548;G01N33/579;G03C7/407 |
主分类号 |
G03C5/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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