发明名称 |
8-substituerte-9H-1,3-Dioxolo/4,5- h//2,3/benzodiazepinderivater, som AMPA/KAINAT reseptorinhibitorer |
摘要 |
The disclosure relates to a novel 8-substituted-9H-1,3-dioxolo-[4,5-h][2,3]benzodiazepine compound of formula I and pharmaceutically acceptable quaternary ammonium salts thereof, a process for preparing the same, a pharmaceutical composition containing a 8-substituted-9H-1,3-dioxolo-[4,5-h][2,3]benzodiazepine compound, and a method of treatment using the pharmaceutical composition. A complete description of the compound of formula I is found in the specification. The compounds of the general formula I possess unique competitive AMPA/kainite antagonist properties making them useful in the treatment of diseases where inhibition of the AMPA/kainite receptors may a favorable effect. |
申请公布号 |
NO20000655(D0) |
申请公布日期 |
2000.02.09 |
申请号 |
NO20000000655 |
申请日期 |
2000.02.09 |
申请人 |
EGIS GYOGYSZERGYSR RT |
发明人 |
RSTKAI, ZOLTSN;BARKOCZY, JOZSEF;SCHNEIDER, GEZA;CSELENYOK, JUDIT;SIMIG, GYULA;BALSZS, LSSZLO;DOMSN, IMRE;GREFF, ZOLTSN;NAGY, PETER KOTAY;SERES, PETER |
分类号 |
A61K31/551;A61P1/08;A61P21/02;A61P25/00;A61P25/06;A61P25/08;A61P25/28;C07D491/04;C07D491/056;(IPC1-7):C07D |
主分类号 |
A61K31/551 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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