| 发明名称 |
BROMODOMAIN INHIBITORS. |
| 摘要 |
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease. |
| 申请公布号 |
MX2016005038(A) |
申请公布日期 |
2016.09.13 |
| 申请号 |
MX20160005038 |
申请日期 |
2014.10.17 |
| 申请人 |
CELGENE QUANTICEL RESEARCH INC. |
发明人 |
Michael John BENNETT;Juan Manuel BETANCORT;Amogh BOLOOR;Stephen W. KALDOR;Jeffrey Alan STAFFORD;James Marvin VEAL |
| 分类号 |
C07D498/04;C07D211/94;C07D217/24;C07D401/04;C07D405/04;C07D413/04;C07D471/04;C07D487/04 |
主分类号 |
C07D498/04 |
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