发明名称 |
Compositions and methods for the treatment of infections and tumors |
摘要 |
Disclosed is the use of activated T cells and a PD-1 antagonist in the manufacture of a medicament for inducing an immune response to a tumor antigen of interest in a mammalian subject having a tumor for treating said tumor, wherein the T cells specifically recognize the tumor antigen of interest and wherein the tumor is a colon cancer. Also disclosed is the use of a Programmed Death (PD-1) antagonist and a tumor antigen or a nucleic acid encoding the tumor antigen in the manufacture of a medicament for treating a mammalian subject having colon cancer. |
申请公布号 |
NZ704295(A) |
申请公布日期 |
2016.06.24 |
申请号 |
NZ20070704295 |
申请日期 |
2007.12.26 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;DANA-FARBER CANCER INSTITUTE INC.;EMORY UNIVERSITY |
发明人 |
SHARPE ARLENE;FREEMAN GORDON;AHMED RAFI;AMARA RAMA |
分类号 |
A61K31/20;A61K31/14;A61K31/18;A61K39/12;A61K39/395;C07K16/28 |
主分类号 |
A61K31/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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