发明名称 PROCESS FOR ISOLATING ENANTIOMERS OF RACEMIC CETAMINE
摘要 The present invention describes a new process for obtainment of the cetamine enantiomers, form the racemic cetamine resolution with the aid of an agent of chiral resolution, which provides the selective crystallization of its enantiomers. The resolution agent is employed in special concentration conditions, which provides stability, reproducibility and high enantiomeric purity to the precipitated diasteromer salt, making feasible the industrial production of the S-cetamine and its pharmaceutically acceptable salts.
申请公布号 WO0198265(A3) 申请公布日期 2002.08.15
申请号 WO2001BR00075 申请日期 2001.06.18
申请人 CRISTALIA PRODUTOS QUIMICOS E FARMACEUTICOS LTDA.;TORRES RUSSO, VALTER, FREIRE;MANNOCHIO DE SOUZA RUSSO, ELISA 发明人 TORRES RUSSO, VALTER, FREIRE;MANNOCHIO DE SOUZA RUSSO, ELISA
分类号 A61P23/00;A61P25/04;C07B57/00;C07C221/00;C07C225/12 主分类号 A61P23/00
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