SENSITIZER FOR ANTICANCER AGENT

摘要

It is clarified that the inhibition of the function or expression of 27 kinds of proteins, which participate in the repair and stabilization of chromosome, results in an effect of potentiating the anticancer effect of a known anticancer agent. Compound which inhibit the function of these 27 kinds of proteins or the expression of genes encoding these proteins are useful as a sensitizer for an anticancer agent. A medicinal composition comprising such a compound as described above makes it possible to reduce the dose of a therapeutic used in treating cancer. Also, this composition is usable as a drug to be combined with an anticancer agent which shows little side effects.