COMPOSITION AND METHOD FOR THE DETECTION OF DISEASES ASSOCIATED WITH AMYLOID-LIKE FIBRIL OR PROTEIN AGGREGATE FORMATION
摘要
The present invention relates to novel compositions useful for elucidating the onset or progress of diseases of preferably neuronal origin associated with the formation of amyloid-like fibrils or protein aggregates. Further, the present invention relates to methods for monitoring said formation as well as to methods for identifying inhibitors of said formation. Additionally, the invention relates to inhibitors identified by the method of the invention as well as to pharmaceutical compositions comprising said inhibitors.
申请公布号
WO9906545(A3)
申请公布日期
1999.08.05
申请号
WO1998EP04811
申请日期
1998.07.31
申请人
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.;WANKER, ERICH;LEHRACH, HANS;SCHERZINGER, EBERHARD;BATES, GILLIAN