摘要 |
<p>A compound represented by the formula (I) ÄA represents a 5- to 7-membered hydrocarbon ring group; L represents -NR<3>-CO-, -CO-NR<3>- and the like (R<3> represents a hydrogen atom, a lower alkyl group, a lower acyl group and the like); M represents an alkylene linking group (a carbon atom constituting the carbon chain may be replaced with a nitrogen atom, an oxygen atom and the like); X represents -S-, -O-, -NR<4>-, -NR<5>-CO- and the like (R<4> and R<5> represent a hydrogen atom, a lower alkyl group and the like) or a single bond; Y represents an alkyl group, an aryl group, an amino group, an aromatic heterocyclic group and the like; R<1> represents a lower alkyl group, a lower alkenyl group, a lower alkynyl group or a lower acyl group; and R<21>, R<22> and R<23> represent a hydrogen atom, a hydroxyl group, a lower alkyl group and the likeÜ or a salt thereof. The compound is useful as an active ingredient of medicaments for diseases in which neuropeptide Y is involved, ingestion control for hyperphagia and the like. <CHEM></p> |
申请人 |
MEIJI SEIKA KAISHA, LTD. |
发明人 |
NISHIKAWA, NAOYUKI;SUGAI, MASAHARU;AOKI, KOZO;SUZUKI, MAKOTO;IKEGAWA, AKIHIKO;TAKAHASHI, KAZUNOBU;OHSAWA, FUKUICHI;MASUDA, NAOMI;KAKUI, NOBUKAZU;TANAKA, JIRO;TABATA, YUJI;ASAI, KENJI |