PHAGE DISPLAY SELECTION SYSTEM FOR FOLDED PROTEINS
摘要
The present invention concerns a method for the selection of a virus comprising the steps of: (a) providing a virus encoding and displaying a fusion polypeptide, said fusion polypeptide comprising a heterologous polypeptide inserted into the sequence of a viral coat protein polypeptide, wherein said virus comprises a cleavable site located within a displayed polypeptide; (b) exposing the virus to a cleaving agent; (c) propagating the virus comprising intact fusion protein.
申请公布号
WO9958655(A3)
申请公布日期
2000.01.27
申请号
WO1999GB01526
申请日期
1999.05.13
申请人
MEDICAL RESEARCH COUNCIL;RIECHMANN, LUTZ;KRISTENSEN, PETER;JESTIN, JEAN-LUC;WINTER, GREGORY, PAUL
发明人
RIECHMANN, LUTZ;KRISTENSEN, PETER;JESTIN, JEAN-LUC;WINTER, GREGORY, PAUL