| 发明名称 | Compositions and methods for treating retrovirus infections | ||
| 摘要 | The present invention relates to at least one nucleic acid (i) comprising or consisting of or (ii) encoding a nucleic acid comprising or consisting of, a sequence selected from the group consisting of: 1) SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, and SEQ ID NO: 4, and 2) a sequence derived from SEQ ID NO: 1 to 4 by substitution deletion or insertion of at least one nucleotide, provided that a nucleic acid consisting of the sequence derived from SEQ ID NO: 1 to 4 is liable to induce HIV-1 expression in latent HIV-1-infected cells, for use as a medicament, in particular for treating retrovirus infections. | ||
| 申请公布号 | US9439923(B2) | 申请公布日期 | 2016.09.13 |
| 申请号 | US200913131313 | 申请日期 | 2009.11.26 |
| 申请人 | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) | 发明人 | Benkirane Monsef;Triboulet Robinson;Chable-Bessia Christine;Bennasser Yamina;Latreille Daniel;Meziane Oussama;Barbry Pascal;Mari Bernard;Reynes Jacques |
| 分类号 | A61P31/18;A61K31/7105 | 主分类号 | A61P31/18 |
| 代理机构 | Blank Rome LLP | 代理人 | Blank Rome LLP |
| 主权项 | 1. A method for inducing HIV-1 expression in latent HIV-1-infected cells in an individual in need thereof comprising administering to the individual a therapeutically effective amount of at least one nucleic acid comprising or encoding a nucleic acid comprising: a sequence selected from the group consisting of: SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3; SEQ ID NO:4, and a combination thereof. | ||
| 地址 | Paris FR | ||