PROCESS FOR THE PREPARATION OF TETRAETHYL METHYLENEBISPHOSPHONATE
摘要
This invention relates to a process for the preparation of tetraethyl methylenebisphosphonate by the reaction of dichloromethane with diethyl phosphite, wherein the reaction is performed in a polar aprotic solvent or mixtures thereof.
申请公布号
WO9733893(A1)
申请公布日期
1997.09.18
申请号
WO1997US03726
申请日期
1997.03.10
申请人
ZENECA LIMITED;LEADBETTER, MICHAEL, R.;BROWN, RICHARD, W.;MCKENNA, MAUREEN, M.
发明人
LEADBETTER, MICHAEL, R.;BROWN, RICHARD, W.;MCKENNA, MAUREEN, M.