PHARMACEUTICAL COMPOSITION FOR DIAGNOSIS, PREVENTION OR TREATMENT OF A TUMOROUS STATE, COMPRISING A MODULATOR OF THE ACTIN POLYMERISATION STATE

摘要

The invention relates to a pharmaceutical composition in the field of oncology, for diagnosis, prevention or treatment of a tumorous state, said pharmaceutical composition comprising an active agent capable of stabilising the actin network of the cellular cytoskeleton, in particular a DNA, coding for the zyxin gene. The invention also relates to a method for identification of compounds capable of stabilising the actin network of the cellular cytoskeleton and, furthermore, a diagnostic method for a tumorous state and a method for analysing the tumoral phenotype of a patient, based on quantification of the expression of zyxin by the cells.