摘要 |
Polymers of structure: <CHEM> in which, n is 0 or 1; m is 1 to 20; Z is H or a group <CHEM> X is 0, S, SO2, amido or sulphonamido; R<1> and R<2> are the same or different and are each C1-4alkyl; R<3> is C1-20alkyl; or R<1> to R<3> together with the nitrogen atom to which they are attached form a ring, optionally containing one or more further heteroatoms and optionally substituted by a C1-4alkyl group; a, b and c are numbers which indicate the relative molar percentages of the units present in a random distribution in said polymer, (b) being from about 0.5 to about 10 molar percent, and (c) being from about 30 to about 99 molar percent; and Y(-) is a physiologically acceptable counter ion, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as cholesterol lowering agents. |