| 发明名称 | Compositions and uses thereof | ||
| 摘要 | Provided are solid dispersions, solid molecular complexes, salts and crystalline polymorphs involving propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide. | ||
| 申请公布号 | US9447089(B2) | 申请公布日期 | 2016.09.20 |
| 申请号 | US201012752035 | 申请日期 | 2010.03.31 |
| 申请人 | Plexxikon Inc.;Hoffman-La Roche Inc. | 发明人 | Desai Dipen;Diodone Ralph;Go Zenaida;Ibrahim Prabha N.;Iyer Raman;Mair Hans-Juergen;Sandhu Harpreet K.;Shah Navnit H.;Visor Gary;Wyttenbach Nicole;Lauper Stephan;Pudewell Johannes;Wierschem Frank |
| 分类号 | A61K9/14;C07D471/04;A61K31/437;A61K9/10;A61K9/16;A61K9/00 | 主分类号 | A61K9/14 |
| 代理机构 | Sheppard Mullin Richter & Hampton LLP | 代理人 | Sheppard Mullin Richter & Hampton LLP |
| 主权项 | 1. A solid dispersion comprising Compound I having the formula:wherein Compound I is molecularly dispersed within a polymer matrix formed by hydroxypropylmethyl cellulose acetate succinate (HPMCAS) in its solid state, and wherein Compound I is substantially amorphous. | ||
| 地址 | Berkeley CA US | ||