发明名称 |
composto, medicamento, uso de um composto, composição farmacêutica, e, processo para preparar composto |
摘要 |
Embodiments of the invention relate to (5R)-1,5-diaryl-4,5-dihydro-1H-pyrazole-3-carboxamidine derivatives as cannabinoid-CB1 receptor antagonists, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of said dihydropyrazole derivatives, to methods for the preparation of these intermediates, pharmaceutical compositions containing one or more of these dihydropyrazole derivatives as an active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of psychiatric and neurological disorders involving cannabinoid receptors. The compounds of embodiments of the invention are compounds of formula (I) wherein the symbols have the meanings given in the specification. |
申请公布号 |
BRPI0911222(A2) |
申请公布日期 |
2016.10.18 |
申请号 |
BR2009PI11222 |
申请日期 |
2009.04.22 |
申请人 |
ABBOTT HEALTHCARE PRODUCTS B.V. |
发明人 |
ARNOLD P. DEN HARTOG;BERNARD J. VAN VLIET;JOSEPHUS H. M. LANGE |
分类号 |
C07D401/12;A61K31/4155;A61K31/454;A61P25/00;C07D403/12 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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