发明名称 |
Pharmaceutical composition having site-specific delivery |
摘要 |
PCT No. PCT/NL93/00061 Sec. 371 Date Nov. 4, 1994 Sec. 102(e) Date Nov. 4, 1994 PCT Filed Mar. 15, 1993 PCT Pub. No. WO93/17713 PCT Pub. Date Sep. 16, 1993Use of alpha -hydroxy acids and poly- alpha -hydroxy acids as spacer between a therapeutically and/or diagnostically active compound and a soluble macromolecular carrier in pharmaceutical compositions having site-specific delivery. In one embodiment glycolic acid, L-lactic acid or tetra-L-lactic acid is used as spacer between a non-steroidal anti-inflammatory substance and a carrier of low molecular protein (LMWP).
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申请公布号 |
US5753611(A) |
申请公布日期 |
1998.05.19 |
申请号 |
US19940302749 |
申请日期 |
1994.11.04 |
申请人 |
RIJKSUNIVERSITEIT GRONINGEN |
发明人 |
FRANSSEN, ERIK J. F.;MOOLENAAR, FRITS;MEIJER, DIRK K. F.;DE ZEEUW, DICK |
分类号 |
A61K9/00;A61K31/19;A61K45/00;A61K47/48;A61P29/00;(IPC1-7):A61K38/00;A61K31/22;A61K31/185 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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