发明名称 Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives
摘要 A process for preparing N4-acyl-5'-deoxy-5-fluorocytidine derivatives of formula III: <IMAGE> III by selective deacylation, wherein R is alkyl, cycloalkyl, alkenyl, aralkyl or aryl, which comprises reacting a compound of formula II, <IMAGE> II wherein R is as defined above, with a base in an aqueous or inert organic solvent.
申请公布号 US5476932(A) 申请公布日期 1995.12.19
申请号 US19940296842 申请日期 1994.08.26
申请人 HOFFMANN-LA ROCHE INC. 发明人 BRINKMAN, HERBERT R.;KALARITIS, PANAYIOTIS;MORRISSEY, JOHN F.
分类号 A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61P35/00;C07H19/06;(IPC1-7):C07H1/00;C07H19/067 主分类号 A61K31/70
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