发明名称 |
Solutions comprising polyethylene glycol and electrolytes |
摘要 |
A solution in water comprising the following components at the following concentrations: (a) N×(70 to 130) g/L polyethylene glycol (PEG) having an average molecular weight of 2500 to 4500; (b) N×(1.6 to 4.0) g/L sodium chloride; (c) N×(0.2 to 0.6) g/L potassium chloride; (d) N×(0.6 to 2.2) g/L sodium bicarbonate; (e) N×an amount of preservative; (f) optionally N x an amount of flavouring; and (g) optionally N×an amount of sweetener, where N is in the range of 2 to 8. The solution is a concentrate for dilution. In use it is diluted N-fold with water to provide a solution for administration to a subject for the treatment of constipation or faecal impaction. Also provided are solutions, kits, unit doses and methods that comprise or use the solutions. |
申请公布号 |
US9468686(B2) |
申请公布日期 |
2016.10.18 |
申请号 |
US201414166716 |
申请日期 |
2014.01.28 |
申请人 |
NORGINE BV |
发明人 |
Seldon Chris;Padfield Dawn;Morrissey Frances |
分类号 |
A61K47/14;A61K31/08;A61K47/10;A61K33/14;A61K9/00 |
主分类号 |
A61K47/14 |
代理机构 |
Yankwich & Associates, P.C. |
代理人 |
Yankwich & Associates, P.C. ;Yankwich Leon R.;Wesolowski Michael R. |
主权项 |
1. A solution in water comprising the following components at the following concentrations:
(a) N×(70 to 130) g/L polyethylene glycol (PEG) having an average molecular weight of 2500 to 4500; (b) N×(1.6 to 4.0) g/L sodium chloride; (c) N×(0.2 to 0.6) g/L potassium chloride; (d) N×(0.6 to 2.2) g/L sodium bicarbonate; and (e) a preservative comprising methyl paraben, ethyl paraben and benzyl alcohol;where N is in the range of 2 to 8. |
地址 |
Amsterdam Zuid-Oost NL |