NOVEL 2,6-DIAMINOPYRIMIDINE DERIVATIVE

摘要

To provide a novel 2,6-diaminopyrimidine derivative by the following formula (I):;A 2,6-diaminopyrimidine derivative is represented by the formula (I):;;wherein

R1 represents a substituted or unsubstituted lower alkyl group, or a substituted or unsubstituted alkoxy group,

Ar represents a substituted or unsubstituted aryl group, or a substituted or unsubstituted heteroaryl group,

Z1 and Z2 represent carbon atoms, or either 1 or 2 of the Z1 and Z2 represent nitrogen atoms,

Q is selected from a structure (a) or (b) described below:
;;R2 represents a substituted or unsubstituted lower alkyl group, or a substituted or unsubstituted cycloalkyl group,

R3 represents a hydrogen atom or a halogen atom,

Y represents a nitrogen atom or a carbon atom, and the bond drawn with a dotted line parallel to a solid line on structure (a) represents either double bond or single bond.

主权项

1. A 2,6-diaminopyrimidine derivative represented by the following formula (I): wherein R1 is a substituted or unsubstituted lower alkyl group, or a substituted or unsubstituted alkoxy group, Ar is a substituted or unsubstituted aryl group, or a substituted or unsubstituted heteroaryl group, Z1 and Z2 are each independently a carbon atom or a nitrogen atom, Q is structure (a) or (b): R2 is a substituted or unsubstituted lower alkyl group, or a substituted or unsubstituted cycloalkyl group, R3 is a hydrogen atom or a halogen atom, Y is a nitrogen atom or a carbon atom, and the bond drawn with a dotted line parallel to a solid line on structure (a) is a double bond or single bond, or a pharmaceutically acceptable salt thereof.