| 发明名称 |
Sustained Release Formulations Containing Methylglyoxal and Their Therapeutic Applications |
| 摘要 |
Provided herein is a nano drug composition for the treatment of cancer including 0.125-0.5 mg of methylglyoxal as conjugated to nanoparticles of chitosan, its derivatives, or other polymers; 25-100 mg of ascorbic acid; 75-300 mg of creatine; and 0.125-0.5 mg of melatonin, wherein all constituents are meant for each kg of body weight. |
| 申请公布号 |
US2016243056(A1) |
申请公布日期 |
2016.08.25 |
| 申请号 |
US201315026393 |
申请日期 |
2013.10.01 |
| 申请人 |
RAY MANJU;VERMA JITENDRA NATH;VERMA LILY |
发明人 |
Ray Manju;Verma Jitendra Nath;Verma Lily |
| 分类号 |
A61K31/12;A61K47/48;A61K31/375;A61K9/48;A61K31/4045;A61K31/198 |
主分类号 |
A61K31/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition, comprising:
0.125-0.5 mg of methylglyoxal encapsulated by or conjugated to nanoparticles, dendrimers of biodegradable synthetic polymers, natural polymers and their derivatives; 0.125-0.5 mg of melatonin; 75-300 mg of creatine; and 25-100 mg of ascorbic acid, wherein all constituents are meant for each kg of body weight. |
| 地址 |
Kolkata IN |
