发明名称 |
NOVEL HUMAN TRANSMEMBRANE 4 SUPERFAMILY PROTEIN |
摘要 |
The present invention provides a novel human integral membrane (TMP-1) and polynucleotides which identify and encode TMP-1. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding TMP-1 and a method for producing TMP-1. The invention also provides for agonists, antibodies, or antagonists specifically binding TMP-1, and their use, in the prevention and treatment of diseases associated with expression of TMP-1. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding TMP-1 for the treatment of diseases associated with the expression of TMP-1. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding TMP-1.
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申请公布号 |
CA2282736(A1) |
申请公布日期 |
1998.09.03 |
申请号 |
CA19982282736 |
申请日期 |
1998.02.18 |
申请人 |
INCYTE PHARMACEUTICALS, INC. |
发明人 |
HILLMAN, JENNIFER L.;GOLI, SURYA K. |
分类号 |
C12N15/09;A61K38/00;A61K39/395;A61K45/00;A61P35/00;A61P35/04;C07K14/705;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12Q1/68;(IPC1-7):C12N15/12 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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