发明名称 Substituted benzoate derivatives
摘要 The present invention relates to the compounds of the formula: <IMAGE> in which R1, R2, R3, R4, R5, R6, R7, and R8 are independently hydrogen, lower alkyl which is optionally substituted, lower alkoxy which is optionally substituted, hydroxy, acyloxy, or halogen; R9 is hydrogen, hydroxy, acyloxy, lower alkyl which is optionally substituted, lower alkoxy which is optionally substituted, or lower alkylamino which is optionally substituted; E1 is hydrogen, or an ester residue; m is an integer of from 1 to 4; or a pharmaceutically acceptable salt thereof. The compounds of the present invention exhibit phospholipase A2 inhibitory activity, and can be used in treating inflammatory conditions.
申请公布号 US5473096(A) 申请公布日期 1995.12.05
申请号 US19930093953 申请日期 1993.07.21
申请人 SHIONOGI & CO., LTD. 发明人 MATSUTANI, SHIGERU;YOSHIDA, TADASHI;SAKAZAKI, RYUJI;FUJII, YASUHIKO;TANAKA, KAZUSHIGE
分类号 A61K31/235;A61K31/24;A61P29/00;A61P43/00;C07C69/86;C07C69/92;C07C69/94;C07C219/22;C07C229/38;C07C237/06;C07C271/22;(IPC1-7):C07C229/36 主分类号 A61K31/235
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