| 主权项 |
1. A method for preparing a powdered extracellular matrix material, the method. comprising the steps of:
mixing extracellular matrix material, after removal of cells from the extracellular matrix material, a crystalline material, and an aqueous medium; then precipitating the crystalline material out of the aqueous medium to provide the crystalline material associated with the extracellular matrix material wherein the crystalline material is in solution before the precipitation step; wherein the mixing followed by the precipitation results in imbedded crystalline material with the extracellular matrix material; drying the extracellular matrix material with the associated crystalline material precipitate to provide the dried extracellular matrix material; comminuting the dried extracellular matrix material including the associated crystalline material into a powder form extracellular matrix material; and removing the crystalline material from the powder form extracellular matrix material, wherein the extracellular matrix material is selected from the group consisting essentially of small intestinal submucosa tissue, urinary bladder submucosa tissue, stomach submucosa tissue, and liver basement membrane tissue. |
