CONTROLLED RELEASE DOSAGE FORMS HAVING A DEFINED WATER CONTENT

摘要

A controlled release, solid, oral dosage form containing a 3-alkylxanthine, preferably theophylline, at least one hydrophilic or hydrophobic polymer, at least one wax having a melting point between 25.degree. and 90.degree.C and between 3% and 10% (by weight) water. Preferably the dosage form is a tablet and the water content is between 9% and 9% (by weight). The amount of water present in the dosage form determines the rate of release of the 3-alkylxanthine.