Simplified storage of at least one test element including a dry reagent layer having an enzyme and a stabilized coenzyme

摘要

Storage containers for storing at least one diagnostic test element including an enzyme and a stabilized coenzyme are disclosed. In addition, diagnostic products which include diagnostic test elements including an enzyme and a stabilized coenzyme, as well as analytical measuring devices which include such storage containers or diagnostic products, are also disclosed. Other aspects include, but are not limited to, unique methods, techniques, products, systems and devices involving test elements which include an enzyme and a stabilized coenzyme.

主权项

1. A storage container, comprising:
at least one diagnostic test element including a dry reagent layer comprising an enzyme and a stabilized coenzyme, wherein the storage container (a) is essentially free of desiccants and (b) comprises no sealing elements which substantially prevent penetration of moisture from an environment into the storage container, wherein the stabilized coenzyme stabilizes the enzyme, wherein the enzyme is a dehydrogenase, and wherein the stabilized coenzyme is a compound of general formula (I): in which A=adenine or an analogue thereof; T=in each case independently denotes O or S; U=in each case independently denotes OH, SH, BH3−, or BCNH2−; V=in each case independently denotes OH or a phosphate group, or two groups which form a cyclic phosphate group; W═COOR, CON(R)2, COR, or CSN(R)2 in which R in each case independently denotes H or a C1-C2 alkyl; X1, X2=in each case independently denote O, CH2, CHCH3, C(CH3)2, NH, or NCH3; Y═NH, S, O, or CH2; Z=a linear residue or a cyclic organic residue, provided that Z and the pyridine residue are not linked by a glycosidic bond, or a salt or optionally a reduced form thereof.