发明名称 |
NOVEL K04-0144 SUBSTANCES AND PROCESS FOR PRODUCTION THEREOF |
摘要 |
<p>Amicroorganism represented by a strain K04-0144 belonging to Streptomyces sp. having ability to produce K04-0144 substance is cultured in the medium, and the isolated K04-0144A substance, K04-0144B substance and K04-0144C substance therefrom have strong antibacterial activities against Gram-positive bacteria including methicillin-resistant Streptococcus aureus (MRSA), consequently these are useful as the therapeutic agents for infectious disease caused by MRSA as well as infectious diseases caused by multidrug including ²-lactam antibiotics resistant bacteria. Further, similarly, since the novel K04-0144D substance isolated from the cultured liquid has the action for enhancing the effect of ²-lactam antibiotics, which are utilized as the antibacterial agents, in combination with them, it is useful as the therapeutic agent for infectious diseases caused by methicillin-resistant Staphylococcus aureus (MRSA) and multidrug including ²-lactam antibiotics resistant bacteria.</p> |
申请公布号 |
EP2019147(A1) |
申请公布日期 |
2009.01.28 |
申请号 |
EP20060732665 |
申请日期 |
2006.05.16 |
申请人 |
THE KITASATO INSTITUTE |
发明人 |
TOMODA, HIROSHI;KIM, YONG-PIL;HANAKI, HIDEAKI;MATSUMOTO, ATSUKO;TAKAHASHI, YOKO;OMURA, SATOSHI |
分类号 |
C12P19/26;A61K31/7024;A61P31/04;C07H11/04 |
主分类号 |
C12P19/26 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|