发明名称 Hydantoin derivatives useful as metalloproteinase inhibitors
摘要 Disclosed is a compound of formula (I), or a pharmaceutically acceptable salts thereof, wherein R1 is C2-4alkyl and is substituted by two or more fluorine groups, and R2 is methyl or ethyl. Also disclosed is a process for preparing the compound, and the use of the compound for treating conditions mediated by one or more metalloproteinase enzymes or by collagenase 3, such as osteoarthritis or rheumatoid arthritis.
申请公布号 NZ555684(A) 申请公布日期 2009.11.27
申请号 NZ20050555684 申请日期 2005.12.14
申请人 ASTRAZENECA AB 发明人 WATERSON, DAVID;PERSSON, DAVID JONAS
分类号 C07D401/12;A61K31/4166;A61K31/445;A61P19/02 主分类号 C07D401/12
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