<p>Disclosed herein are new immunotherapy methods that involve the isolation of cancer stem cells from tumor tissue and use of the cells either directly or indirectly through proteins or other factors associated with the cells to activate antigen presenting cells. The activated antigen presenting cells are useful as a therapy against the tumor. Also disclosed herein are novel methods of isolating and characterizing cancer stem cells and producing individual cancer stem cell lines. Dendritic cell lines are also disclosed herein.</p>
申请公布号
WO2010011893(A1)
申请公布日期
2010.01.28
申请号
WO2009US51646
申请日期
2009.07.24
申请人
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.;SUGAYA, KIMINOBU;ALVAREZ, ANGEL;BUSHNEV, SERGEY;AVGEROPOULOS, NICHOLAS, G.
发明人
SUGAYA, KIMINOBU;ALVAREZ, ANGEL;BUSHNEV, SERGEY;AVGEROPOULOS, NICHOLAS, G.