ASPIRIN-CONTAINING PHARMACEUTICAL AGENT

摘要

Disclosed is a pharmaceutical agent effective for the prevention and/or treatment of a disease associated with the formation of a thrombus or embolus or a disease induced by the formation of a thrombus or embolus. The pharmaceutical agent comprises a combination of aspirin and any one of the following compounds (a) to (d): (a) a compound capable of acting on a calcium handling protein to modulate the intracellular calcium level or the rate of change in intracellular calcium level; (b) a compound capable of inhibiting the over-accumulation of a calcium ion in a cell; (c) a compound capable of inhibiting the over-accumulation of a sodium ion in a cell; and (d) an aminobenzenesulfonic acid derivative represented by the general formula (I), a salt thereof, or a hydrate or solvate of the derivative or the salt. (I) wherein R<SUB>1</SUB> represents a C<SUB>1</SUB>-C<SUB>6</SUB> alkyl group or the like; R<SUB>2</SUB> represents a hydrogen atom or the like; and n represents an integer of 1 to 4.