THERAPEUTIC AND DIAGNOSTIC METHODS FOR AUTISM SPECTRUM DISORDERS AND OTHER CONDITIONS

摘要

The present invention relates to the field of autism. More specifically, the present invention provides methods for treating individuals with autism spectrum disorders. The present invention also provides methods for predicting a likelihood of ASD. In one embodiment, a method for treating a female patient having a high risk factor of having children with ASD comprises the steps of (a) identifying in a sample taken from the female patient the presence of AT-1 antibodies; and (b) administering an effective amount of an AT-1 inhibitor or inhibitor of AT-1 antibodies to the female patient.

主权项

1. A method of screening a female patient for a high risk of having children with an autism spectrum disorder (ASD) comprising the steps of:
a. obtaining a sample from the female patient; b. detecting the presence of antibodies specific for angiotensin II type 1 receptor (AT-1) in the sample; and c. identifying the female patients as having a high risk of having children with ASD if the AT-1 antibodies are present.