发明名称 |
VERFAHREN ZUM ÜBERWACHEN DES EFFEKTS VON KATHEPSIN-S-INHIBITOREN |
摘要 |
The present invention relates to a method for monitoring the effect of in vivo administration of Cathepsin S inhibitors by measuring accumulation of an intermediate degradation product of invariant chain (Ii), in particular the p10 Ii fragment, in blood of dosed subjects. |
申请公布号 |
DE60130784(T2) |
申请公布日期 |
2008.07.17 |
申请号 |
DE2001630784T |
申请日期 |
2001.08.24 |
申请人 |
ORTHO-MCNEIL PHARMACEUTICAL INC. |
发明人 |
THURMOND, ROBIN;SUN, SIQUAN;KARLSSON, LARS |
分类号 |
G01N33/53;G01N33/535;C12Q1/37;G01N33/545;G01N33/573 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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