发明名称 |
CLARITHROMYCIN-CONTAINING DRIED LIPOSOME COMPOSITION |
摘要 |
PURPOSE: A clarithromycin-containing dried liposome composition is provided. The composition promotes coefficient of utilization of clarithromycin in vivo by solubilizing clarithromycin, putting off a loss thereof in vivo and minimizing pain when injecting, and is superior in physical and chemical stability. CONSTITUTION: A clarithromycin-containing dried liposome composition is composed of clarithromycin of 0.5-30 wt.% as a main element, oil of 0.2-10 wt.%, preferably 2-5 wt.%, phospholipid of 1.2-60 wt.%, preferably, 45-60 wt.%, cholesterol of 0.5-20 wt.%, preferably 5-10 wt.% and filler for preparing dried liposome of 2.1-50 wt. %. The clarithromycin-containing dried liposome composition is prepared by applying dehydration-rehydration method.
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申请公布号 |
KR20000073825(A) |
申请公布日期 |
2000.12.05 |
申请号 |
KR19990017373 |
申请日期 |
1999.05.14 |
申请人 |
EYUN PHARM CO.,LTD. |
发明人 |
KIM, JONG KOOK;KO, JONG HO;KIM, MOON HEE;LEE, MI KYUNG;LEE, SA WON;PARK, JUNG SOOK;KIM, YANG BAE |
分类号 |
A61K31/70;(IPC1-7):A61K31/70 |
主分类号 |
A61K31/70 |
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