发明名称 |
SIMIAN ADENOVIRUSES SAdV-36, -42.1, -42.2, AND -44 AND USES THEREOF |
摘要 |
An adenovirus is disclosed, having a capsid comprising a hexon protein of SAdV-42.1 or an amino acid sequence at least about 99% identical thereto, or a hybrid hexon protein. The capsid encapsidates a heterologous nucleic acid molecule carrying a gene sequence operably linked to expression control sequences which direct transcription, translation, and/or expression in a host cell, and further encapsidates 5' and 3' adenovirus cis-elements necessary for replication and encapsidation. |
申请公布号 |
EP2325298(B1) |
申请公布日期 |
2016.10.05 |
申请号 |
EP20100186684 |
申请日期 |
2009.03.03 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
WILSON, James M.;VANDERBERGHE, Luk;ROY, Soumitra |
分类号 |
C12N7/00 |
主分类号 |
C12N7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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