| 发明名称 |
BIOACTIVE RECOMBINANT BMP-9 PROTEIN, MB109, EXPRESSED AND ISOLATED FROM BACTERIA |
| 摘要 |
The disclosure provides for the expression and purification of bioactive recombinant bone morphogenetic protein (BMP)-9 from bacteria (MB109) and the use of the MB109 to treat various diseases and disorders, including cancer and obesity associated disorders. |
| 申请公布号 |
US2016257728(A1) |
申请公布日期 |
2016.09.08 |
| 申请号 |
US201415029610 |
申请日期 |
2014.10.16 |
| 申请人 |
JOINT CENTER FOR BIOSCIENCES |
发明人 |
Choe Senyon;Kuo Mario Meng-Chiang;Jung Jae Woo;Lee Dong Kun |
| 分类号 |
C07K14/51 |
主分类号 |
C07K14/51 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A protein comprising two or more polypeptides having at least 90% sequence identity to SEQ ID NO:2 and having a methionine at position 1, wherein the protein has human bone morphogenic-9 (human BMP-9) activity. |
| 地址 |
Yeonsu-ku, Incheon KR |
