发明名称 Adamantane or Pinene Derivatives for Use in the Treatment of Chlamydiales Infections
摘要 The present invention relates to a method for treating a Chlamydiales infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof:;W—L1—NH—L2—Ar  (I);Wherein W, L1, L2 and Ar are as defined in claim 1.
申请公布号 US2016310448(A1) 申请公布日期 2016.10.27
申请号 US201615134373 申请日期 2016.04.20
申请人 Commissariat a l'Energie Atomique et aux Energies Alternatives 发明人 Gillet Daniel;Barbier Julien;Cintrat Jean-Christophe;Pons Valérie;Rudel Thomas;Herweg Jo-Ana;Fischer Annette
分类号 A61K31/137 主分类号 A61K31/137
代理机构 代理人
主权项 1. A method for treating a Chlamydiales infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof W—L1—NH—L2—Ar  (I) Wherein: W is independently selected from: an adamantyl optionally substituted by one or more C1-C6 alkyl groups, ora saturated pinanyl L1 is independently selected from a single bond W—N, —(CH2)pC(═O)—, L2 is independently selected from —(CH2)q—, [—C(═O)—NH]r—N═CH—, or —(C6H4)—SO2—NH—, Ar is a C6-C10 aryl or a 5 to 10 membered heteroaryl, said aryl or heteroaryl groups being optionally substituted by one to three R groups, R is independently selected from F, Cl, Br, I, C1-C6 alkyl, C1-C6 alkoxy, NO2, p is 0, 1, or 2, q is 1 or 2, r is 0 or 1, and the stereoisomeric forms, mixtures of stereoisomeric forms or pharmaceutically acceptable salts forms thereof.
地址 Paris FR