| 摘要 |
The invention generally relates to disease detection and medical diagnosis. More particularly, the invention relates to novel systems and methods for detecting Clostridium difficile toxins and related diseases and disorders. In one aspect, the invention generally relates to a method for detecting one or more Clostridium difficile toxins in a subject, comprising contacting a sample from a subject with monoclonal anti-TcdB or anti-TcdA F(ab)2 fragments projecting outwardly; and detecting the presence or absence of TcdB or TcdA by discerning the sample for an agglutination reaction, wherein agglutination indicates the presence of TcdB or TcdA in the sample. In yet another aspect, the invention generally relates to a kit useful for detecting one or more Clostridium difficile toxins, comprising a probe disclosed herein. |
