发明名称 |
PYRAZOLO-PYRAZINES DERIVATIVES USED AS G PROTEIN INHIBITORS |
摘要 |
<p>The invention relates to pyrazolo-pyrazines derivatives of the general formula (I) in which the radicals Z, R1, R2, R3 and R4 represent various variable groups, X is a sulphur atom or a selenium atom, and n is an integer equal to 1 or 2. These compounds are inhibitors of G proteins. They are of particular interest for treating diseases in which the heterotrimeric G protein is involved. The invention also relates to pharmaceutical compositions containing said products, and to the use thereof for preparing a drug.</p> |
申请公布号 |
WO2009074743(A1) |
申请公布日期 |
2009.06.18 |
申请号 |
WO2008FR01332 |
申请日期 |
2008.09.25 |
申请人 |
IPSEN PHARMA S.A.S.;LAVERGNE, OLIVIER;BREHU, LAETITIA;PREVOST, GREGOIRE |
发明人 |
LAVERGNE, OLIVIER;BREHU, LAETITIA;PREVOST, GREGOIRE |
分类号 |
C07D487/04;A61K31/4985;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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