POLYMER-FREE COATINGS FOR MEDICAL DEVICES FORMED BY PLASMA ELECTROLYTIC DEPOSITION

摘要

Methods for the application of a polymer-free coating onto a medical device using plasma electrolytic deposition, comprising: (i) optionally applying a metal precoating onto a medical device; (U) placing the medical device in an electrolyte solution comprising an electrolyte; and (Ui) establishing an electric potential under plasma electrolytic deposition conditions between an electrode and the medical device, such that the plasma electrolytic deposition conditions are adequate to sustain deposition from the electrolyte solution onto the surface of the medical device to form the coating. The invention also relates to coating compositions and coated medical devices, such as stents, made according to these methods. If desired, the polymer-free coating can be a drug-eluting coating.