发明名称 NEUTRALIZING ANTIBODIES TO GP120 AND THEIR USE
摘要 Antibodies and antigen binding fragments that specifically bind to gp120 and neutralize HIV-1 are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.
申请公布号 WO2016154003(A1) 申请公布日期 2016.09.29
申请号 WO2016US23145 申请日期 2016.03.18
申请人 THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES 发明人 CONNORS, Mark;HUANG, Jinghe;KANG, Byong, Ha;MASCOLA, John;ISHIDA, Elise;ZHOU, Tongqing;KWONG, Peter;ZHENG, Anqi
分类号 C07K16/10;A61P31/18 主分类号 C07K16/10
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