HSP20 Inhibits Amyloidogenesis and Neurotoxicity

摘要

The present inventions are compositions and methods of using at least a portion of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.

主权项

1. An isolated and purified polypeptide comprising a fusion protein that comprises a portion of an α-crystallin polypeptide comprising one or more β-pleated sheets that inhibits neurotoxicity and amyloidogenesis and a peptide for isolating the fusion protein.