发明名称 AGENT FOR TREATING OSTEOMYELITIS
摘要 FIELD: pharmaceutics.SUBSTANCE: invention relates to pharmaceutical industry, namely to an agent for treating osteomyelitis. It is suggested to use β-betulonic acid alanylamide of formula (I):as an agent for treating osteomyelitis.EFFECT: presented agent effectively prevents generalization of inflammatory process, formation of extensive zones of necrosis and infiltration, osteoclastic bone resorption and formation of sequestra, which in turn prevents the chronic inflammatory process and enables its elimination; promotes earlier and more expressed formation of loose fibrous connective and membrane reticulated bone in comparison to groups without using betamide, which indicates the positive effect of the preparation on the repair processes in bone; causes faster onset of functional adaptation phase, promoting faster completion of endochondral osteohistogenesis to form trabecular bone tissue.1 cl, 59 dwg, 3 tbl
申请公布号 RU2604124(C1) 申请公布日期 2016.12.10
申请号 RU20150146560 申请日期 2015.10.28
申请人 Federalnoe gosudarstvennoe bjudzhetnoe uchrezhdenie nauki Novosibirskij institut organicheskoj khimii imeni N.N. Vorozhtsova Sibirskogo otdelenija Rossijskoj akademii nauk (NIOKH SO RAN) 发明人 Tolstikova Tatjana Genrikhovna;Sorokina Irina Vasilevna;ZHukova Natalja Anatolevna;Popov Sergej Aleksandrovich;Kozlova Ljubov Pavlovna;SHults Elvira Eduardovna;ZHurakovskij Igor Pavlovich;Autenshljus Aleksandr Isaevich;Marinkin Igor Olegovich
分类号 A61K31/56;A61K31/015;A61P19/08;A61P31/04 主分类号 A61K31/56
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