METHODS AND COMPOSITIONS FOR PRION DECONTAMINATION
摘要
The invention relates to compositions and methods for prion degradation, decontamination or disinfection. The composition comprises an oxidizing agent, one or more proteases and a surfactant such as an ionic surfactant/detergent. The method comprises contacting a prion contaminated entity with a prion-degrading composition comprising an effective amount of an oxidizing agent, an effective amount of at least one protease, and an effective amount of a surfactant. The components of the composition may be contacted with a prion-contaminated entity sequentially or simultaneously using an aqueous composition. Typically at least two different proteases are used for optimal efficacy. Preferably the oxidizing agent comprises peracetyl ions or a source thereof. The invention also relates to kits comprising the various reagents.
申请公布号
WO2008057293(A3)
申请公布日期
2008.07.17
申请号
WO2007US22750
申请日期
2007.10.26
申请人
E. I. DU PONT DE NEMOURS AND COMPANY;CROUD, VINCENT, BRIAN;JACKSON, GRAHAM;COLLINGE, JOHN
发明人
CROUD, VINCENT, BRIAN;JACKSON, GRAHAM;COLLINGE, JOHN