IMPROVED METHOD OF MEASURING AN INTERACTION BETWEEN MOLECULES

摘要

The present invention relates to a method for suppressing background signals in a method or assay comprising providing a test compound in a solution comprising at least one detergent. The present invention further provides an improved and more accurate assay, particularly a competition assay, of determining an interaction between a target compound and a test compound in the presence of a detergent, based on the monitoring of the localized surface plasmon resonance (LSPR) properties of metallic nanoparticles.