发明名称 SPIRO PEPERIDINES AND HOLOLOGS WHICH PROMOTE RELEASE OF GROWTH HORMONE
摘要 TITLE OF THE INVENTION SPIRO PIPERIDINES AND HOMOLOGS PROMOTE RELEASE OF GROWTH HORMONE There are disclosed certain novel compounds identified as spiro piperidines and homologs which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to treat physiological or medical conditions characterized by a deficiency in growth hormone secretion, such as short stature in growth hormone deficient children, and to treat medical conditions which are improved by the anabolic effects of growth hormone. Growth hormone releasing compositions containing such spiro compounds as the active ingredient thereof are also disclosed.
申请公布号 CA2110672(A1) 申请公布日期 1994.06.12
申请号 CA19932110672 申请日期 1993.12.03
申请人 MERCK & CO., INC. 发明人 CHEN, MENG-HSIN;JOHNSTON, DAVID B. R.;NARGUND, RAVI P.;PATCHETT, ARTHUR A.;TATA, JAMES R.;YANG, LIHU
分类号 C07D221/20;A61K31/435;A61K31/4427;A61K31/4433;A61K31/445;A61K31/455;A61K31/55;A61K31/66;A61K38/00;A61K38/04;A61P3/00;A61P5/00;A61P19/10;A61P43/00;C07D223/32;C07D401/04;C07D401/06;C07D401/10;C07D401/12;C07D401/14;C07D403/06;C07D409/06;C07D409/12;C07D453/02;C07D471/10;C07D491/10;C07D495/10;C07F9/40;C07K1/113;C07K5/023;C07K5/06;C07K5/078;C07K14/575;C07K14/61;(IPC1-7):C07K5/06;C07K5/02 主分类号 C07D221/20
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