发明名称 TEMPERATURE SENSITIVE GEL FOR SUSTAINED DELIVERY OF PROTEIN DRUGS
摘要 <p>Pharmaceutical compositions for the delivery of pharmacologically active proteins are provided by the present invention. The compositions of the present invention comprise a polymeric matrix having thermal gelation properties in which is incorporated a discrete suspension of at least one biologically active macromolecular polypeptide which retains greater than 90 percent of its biological activity. Furthermore, the concentration of the macromolecular polypeptide is greater than 0.5 percent by weight of the composition.</p>
申请公布号 WO1998002142(A1) 申请公布日期 1998.01.22
申请号 US1997013479 申请日期 1997.07.11
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